Three of four have been signed for the main cast of the upcoming Fantastic Four movie. Chicklis will play The Thing, I think he’s too small but the face and acting are right so he could certainly do a good job. I’ve never seen Ioan Gruffud and he’s kinda young for the role of Reed Richards but he looks right so he might be ok.
I don’t know which of the five Chris Evans got the role though and although Jessica Alba is gorgeous I don’t see her as Sue Richard. Rachel McAdams looks the part and she’s been getting great reviews for The Notebook, I think she’s a better choice.
[Update: Alba confirmed]